Almost 600 premature deaths are expected to occur during the ongoing heatwave affecting England and Wales, according to a new rapid analysis by leading scientists. The majority of fatalities are projected among older adults, with London and the West Midlands likely to be the worst-affected areas.
Climate change driving deadly temperatures
Researchers say the extreme temperatures, which have reached 32°C in parts of south-east England, would have been nearly impossible without the influence of human-caused climate change. Pollution from burning fossil fuels has raised the likelihood of such heatwaves by around 100 times, experts say.
The scientists estimate that human activity has increased the temperatures experienced during this heatwave by 2°C to 4°C, pushing the mercury beyond safe levels for many, particularly the elderly and those with underlying health conditions.
Dr Garyfallos Konstantinoudis from Imperial College London, who helped conduct the analysis, said: “Heatwaves are silent killers – people who lose their lives in them typically have pre-existing health conditions and rarely have heat listed as a contributing cause of death. This real-time analysis reveals the hidden toll of heatwaves, and we want it to help raise the alarm.”
Deaths concentrated among older adults
The analysis, based on decades of UK temperature and mortality data across more than 34,000 locations in England and Wales, projects around 570 excess deaths between Thursday and Sunday. Of these, approximately 129 are expected in London. Scientists believe the figure may be underestimated, as early summer heatwaves often catch people unprepared.
Around 85% of the projected deaths are likely to involve people over the age of 65, who are particularly vulnerable to heat stress. Other at-risk groups include infants, pregnant individuals, and people with cardiovascular or respiratory conditions.
Dr Malcolm Mistry from the London School of Hygiene & Tropical Medicine (LSHTM), who contributed to the study, warned: “Exposure to temperatures in the high 20s or low 30s may not seem dangerous, but they can be fatal, particularly for people aged over 65, infants, pregnant people, and those with pre-existing health conditions.”
Health and emergency services under pressure
The UK Health Security Agency (UKHSA) issued an amber heat-health alert on Thursday, which is set to remain in effect until 9 am on Monday. The warning highlights a risk of increased deaths and severe impacts on health and social care systems.
Medical professionals have reported a rise in heat-related illnesses. Dr Lorna Powell, an urgent care doctor in East London, said: “We are seeing cases of heat exhaustion rising. It can quickly trigger more serious illnesses, as dehydration sets in and the cardiovascular system becomes overwhelmed.”
The UKHSA advises people to stay out of the sun between 11 am and 3 pm, drink plenty of fluids, keep indoor spaces cool, and check in on vulnerable neighbours and family members. Data from a recent study indicates that approximately 80% of UK homes overheat during summer, further exacerbating health risks for residents.
Urban areas face greater risk
City dwellers, especially those in poorly ventilated flats, face higher health risks during heatwaves. Heat becomes trapped in buildings, leading to prolonged exposure, especially at night when outdoor temperatures remain high.
Professor Antonio Gasparrini of LSHTM, another contributor to the analysis, said: “When temperatures push past the limits populations are acclimatised to, excess deaths can increase very rapidly. Every fraction of a degree of warming will cause more hospital admissions and heat deaths, putting more strain on the NHS.”
Poor preparedness criticised
Between 2020 and 2024, more than 10,000 people died in the UK due to heatwaves, according to UKHSA data. Yet in April 2025, the government’s climate advisers criticised the UK’s readiness to deal with extreme heat, calling preparations “inadequate, piecemeal and disjointed”.
Despite growing awareness of climate-related risks, systemic changes to improve resilience, such as retrofitting homes and bolstering healthcare capacity, have been limited.
Government removes barriers to home EV chargers
As part of broader environmental measures, the UK government recently eliminated the requirement for planning permission to install electric vehicle (EV) chargers at homes and businesses. This change is estimated to save an average of £1,100 per installation, according to the Department for Transport, and may aid the shift to low-carbon transport. While unrelated to heatwave policy, the move reflects the government’s push for green infrastructure.
Air quality worsens amid heat
Alongside the heat, a spike in air pollution has raised additional concerns. London has been issued a high ozone pollution alert, with people suffering from respiratory conditions such as asthma advised to avoid outdoor exercise.
Heatwaves becoming more frequent and intense
Global data shows that extreme heat causes more deaths than floods, hurricanes, or earthquakes. According to insurer Swiss Re, heatwaves are responsible for about 500,000 deaths globally each year. “Extreme heat events are more dangerous than natural catastrophes in terms of human lives lost, yet the true cost is only starting to come to light,” said Nina Arquint, chief executive of corporate solutions at Swiss Re.
In 2024, the planet recorded its hottest year on record, driven by climate change and rising emissions. Carbon dioxide levels from fossil fuels continue to increase, pushing the world closer to dangerous temperature thresholds.
A recent report by the UK Climate Change Committee estimates that if global temperatures rise by 2°C above pre-industrial levels, annual heat-related deaths in the UK could exceed 10,000 by 2050.
The scientists behind the current analysis hope that quantifying the hidden human cost of heatwaves will prompt more urgent action to reduce emissions and prepare the UK for a hotter future.
A new weight-loss drug, amycretin, has delivered the most significant results yet for appetite-suppressing GLP-1 medications, according to two newly published studies in The Lancet and presentations at the American Diabetes Association’s 2025 Scientific Sessions in Chicago.
Record weight loss from Amycretin injections
Researchers found that participants receiving high-dose weekly injections of amycretin lost 24.3 per cent of their body weight over 36 weeks. This outcome surpasses the results seen in longer trials involving other GLP-1 drugs such as tirzepatide (sold as Mounjaro), which previously led the field with an average weight loss of 20 per cent over 72 weeks.
Amycretin, developed by Novo Nordisk, the same pharmaceutical company behind Wegovy and the Type 2 diabetes treatment Ozempic, works by targeting both the GLP-1 and amylin receptors. These receptors help control blood sugar levels and suppress appetite.
Strong results for oral version
In addition to the injectable form, a parallel study explored amycretin in tablet form. Conducted over 12 weeks and involving 144 adults, the trial showed those on the highest daily dose (100mg) lost 13.1 per cent of their body weight – a substantial result for an oral medication over such a short period.
Both studies also reported improvements in metabolic and glycaemic health. The authors wrote that amycretin “effectively lowered body weight and improved metabolic and glycaemic parameters in people with overweight or obesity”. They called for longer and larger trials to assess long-term safety and optimise the dosing regimen.
Pills could overtake jabs in the future
While the injectable version delivered record weight loss, the promising results from the pill suggest oral treatments could soon rival or even surpass jabs in convenience and effectiveness.
Health experts have described the development of an effective pill as a potential “game-changer” in tackling obesity. Professor Jason Halford, former president of the European Association for the Study of Obesity, said: “They will be easier to produce, store and use, and this should mean they could become more widely available. That would produce a significant impact on the nation’s health.”
Limited NHS rollout as private demand surges
Obesity remains a major issue in the UK, with around two in three adults considered overweight or obese. The NHS is set to begin prescribing GLP-1 injections from late June 2025, although the initial rollout will be limited. Around 220,000 people are expected to be treated through the NHS within the next three years.
Eligibility criteria are strict, covering only the most obese patients with at least four chronic health conditions linked to excess weight. Meanwhile, private use of these medications has surged, with an estimated 1.5 million people in the UK having already purchased jabs like Wegovy.
Wegovy also shows promise at higher doses
Separately, another study presented at the ADA meeting focused on Wegovy (semaglutide), examining the effects of a higher weekly dose of 7.2mg. This led to average weight loss of 20.7 per cent over 72 weeks, up from 13.7 per cent at the standard dose used in earlier trials.
As competition intensifies in the weight-loss drug market, amycretin’s early results, particularly in tablet form, suggest it could play a major role in the future of obesity treatment.
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Hogan’s current hospital stay follows a neck fusion surgery he underwent in May 2025
WWE Hall of Famer Hulk Hogan has been hospitalised for ongoing neck and back issues, but representatives have confirmed he is not in critical condition, dismissing online speculation suggesting otherwise.
The 71-year-old wrestling icon, whose real name is Terry Bollea, was reported by TMZ Sports to be undergoing treatment related to injuries sustained during his decades-long in-ring career. His representative said Hogan is already mobile again and “not on his deathbed”, following false claims made on air by Florida radio personality Bubba the Love Sponge.
The speculation began after Bubba stated he had heard Hogan’s health had declined significantly and that family members were being called to say their goodbyes. However, he admitted the information was second-hand and unverified at the time of broadcast.
— (@)
In reality, Hogan’s current hospital stay follows a neck fusion surgery he underwent in May 2025, which was described as successful. He has undergone numerous operations over the years to treat wear and tear from wrestling, particularly to his spine, hips and knees.
Despite his physical challenges, Hogan has continued to make public appearances. His most recent confirmed outing was in January 2025 on WWE Raw, where he promoted his Real American Beer brand during the programme’s Netflix launch. The segment received a mixed reaction from the crowd.
Hogan remains one of the most recognisable figures in professional wrestling, having helped define the industry during the 1980s boom. He held multiple world titles and was central to WWE's rise to global popularity, later moving to WCW and becoming a founding member of the nWo.
His team has confirmed there is no cause for alarm, and that his current hospitalisation is part of ongoing care rather than any emergency. No further surgeries have been announced at this stage.
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Several hidden threats linked to heat waves often go unnoticed
As temperatures across the UK continue to rise, so too do the health risks associated with extreme heat. While sunburn and dehydration are well-known dangers, several hidden threats linked to heat waves often go unnoticed. With climate change intensifying the frequency and severity of hot spells, some forecasts suggesting 40 °C days could become a regular feature in the next 12 years, it’s essential to understand these lesser-known risks and how to protect yourself.
1. Skin reactions triggered by common medications
Certain widely-used medications can increase sensitivity to sunlight, making people more prone to rashes, blistering, and sunburn—even on cloudy days. This includes nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, some antibiotics such as doxycycline, statins, antidepressants, and hormone replacement therapy (HRT).
If you are taking these medications, apply a broad-spectrum sunscreen with SPF 30 or higher, wear protective clothing, and limit your exposure to direct sunlight. It’s also worth consulting your pharmacist to confirm whether your medicines are photosensitising.
2. Medication breakdown in high temperatures
Many people are unaware that heat can reduce the effectiveness of certain medications. Medicines stored in hot environments—such as parked cars, near windows, or in steamy bathrooms—may degrade or fail to work properly.
Insulin, for example, can lose potency if not kept within the recommended temperature range. Always check the storage instructions on packaging and use a cool bag or insulated storage when travelling with essential medicines.
3. Strain on the heart and lungs
Heatwaves place added stress on the cardiovascular and respiratory systems. People with pre-existing heart conditions, high blood pressure, or asthma may be particularly vulnerable. According to the UK Health Security Agency (UKHSA), even moderate increases in temperature can result in a rise in emergency service usage and hospital admissions.
If you or someone you care for has a heart or lung condition, monitor symptoms closely during warm spells. Avoid strenuous activity during peak heat hours (typically 11am to 3pm) and stay indoors in a cool environment where possible.
4. Heat exhaustion that escalates into emergency
Heat exhaustion occurs when the body overheats and cannot cool itself effectively. Symptoms include dizziness, muscle cramps, excessive sweating, nausea, rapid pulse, and fainting. If untreated, this can progress to heatstroke, a medical emergency.
According to NHS guidance, anyone showing signs of heat exhaustion should be moved to a cool place, given fluids, and cooled down within 30 minutes. If symptoms persist beyond this period, dial 999 immediately.
5. Dehydration and kidney problems
Excessive heat leads to fluid loss through sweating, increasing the risk of dehydration. For individuals taking medications such as diuretics, ACE inhibitors, lithium, or NSAIDs, the risk of kidney damage becomes more significant when fluids are lost.
To avoid complications, drink plenty of water throughout the day, even if you don’t feel thirsty. Diluted squash and oral rehydration solutions can also help maintain electrolyte balance. Avoid alcohol and excessive caffeine, both of which contribute to fluid loss.
6. Poor sleep and mental health effects
Hot nights can make it difficult to fall and stay asleep, leading to fatigue and irritability. Prolonged heat exposure can also worsen anxiety, agitation, and even contribute to a rise in suicide rates, according to some studies. The psychological toll of repeated extreme weather events is now recognised as a public health issue.
To maintain good sleep hygiene, keep your bedroom cool and ventilated. Close blinds during the day to block out sunlight and open windows in the evening when outdoor temperatures drop. Use light bedding and consider a fan if the room temperature stays below 35 °C.
7. Long-term damage from repeated exposure
Repeated exposure to extreme heat may contribute to chronic health conditions over time. This includes increased risk of kidney disease, cardiovascular strain, and metabolic disorders. UK health experts warn that, without mitigation and adaptation, the number of heat-related deaths could rise significantly in the coming years.
Heatwaves disproportionately affect the elderly, children, outdoor workers, and those with existing health conditions. As such, public awareness and preparedness are key.
Quick protection tips
Stay hydrated: Aim to drink water regularly. Add squash or electrolyte tablets if needed.
Keep medicines cool: Store according to label instructions, away from sunlight and moisture.
Stay indoors during peak heat: Avoid direct sun between 11am and 3pm.
Wear protective clothing: Lightweight fabrics, wide-brimmed hats, sunglasses, and sunscreen (SPF 30+) are all essential.
Keep your home cool: Shut blinds, use fans below 35 °C, and open windows when cooler outside.
Recognise danger signs: Learn the symptoms of heat exhaustion and stroke, and respond quickly.
Why this matters
A yellow heat-health alert is currently in effect across seven regions in England, including London, the Midlands, and the South East. Temperatures are expected to rise to around 32 °C this weekend, which may meet official criteria for a heatwave.
With the UK facing more extreme weather due to climate change, recognising and responding to these hidden health risks can save lives. Whether you're managing your own health, caring for family members, or working outdoors, being prepared for the heat is now more important than ever.
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Adriana was declared brain-dead on 19 February 2025
Adriana Smith, a 31-year-old woman from Atlanta who was declared brain-dead in February, gave birth to a premature baby boy on 13 June while being kept on life support. Smith’s family confirmed that life support will be withdrawn on Tuesday, 17 June.
The child, named Chance, was delivered via emergency caesarean section and weighed around 1 pound 13 ounces at birth. He remains in the neonatal intensive care unit (NICU), with doctors expecting a stable recovery.
“He’s just fighting,” said Smith’s mother, April Newkirk, speaking to local outlet 11Alive. “We just want prayers for him. Just keep praying for him. He’s here now.”
Kept alive due to legal uncertainty
Smith was declared brain-dead on 19 February 2025, after suffering blood clots in her brain. At the time, she was eight weeks pregnant. Her family says that despite her condition, she was kept medically alive due to the interpretation of Georgia’s abortion law, known as the LIFE Act, passed in 2019.
The LIFE Act bans most abortions once a foetal heartbeat is detected, typically around six weeks, and includes limited exceptions such as cases involving medical emergencies. However, the law does not provide explicit guidance in cases involving brain death, which left Smith’s doctors uncertain about legal responsibilities.
Georgia Attorney General Chris Carr has previously stated that the law does not explicitly require hospitals to keep brain-dead pregnant women on life support, describing the legal situation as unclear. Nonetheless, the hospital involved reportedly continued life support out of caution, treating the foetus as a separate patient.
Mixed reactions from advocacy groups
The case of Adriana Smith has reignited debate in the United States over the implications of abortion laws. Anti-abortion advocates supported the hospital’s decision to maintain life support, citing the foetus’s right to life. On the other hand, reproductive rights groups have voiced concern that such legislation can remove critical medical decision-making from families.
Newkirk told 11Alive that although the family may not have chosen to end the pregnancy, they were denied the option to make that choice themselves. “I think all women should have a choice about their body,” she said. “And I think I want people to know that.”
Grieving the loss while welcoming new life
While the birth of Chance brought a glimmer of hope to the family, it has been accompanied by immense grief. Smith’s eldest child, a seven-year-old son, has been told that his mother is “asleep.”
Newkirk said the family had met with doctors to prepare for removing life support, scheduled for 2 p.m. on 17 June. “It’s kind of hard, you know,” she told 11Alive. “It’s hard to process.”
A GoFundMe campaign launched to support Smith’s family has received donations from over 3,800 people, raising more than $145,400 of its $275,000 target.
“I shouldn’t be burying my daughter,” said Newkirk. “My daughter should be burying me.”
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A one-hour delay in sleep routine is linked to a sharper drop in cognition over time, the study found
A night owl, or an evening person with a late sleep-wake cycle, could be at a higher risk of cognitive decline with age compared to an early bird or a morning person, a study has found.
Chronotype refers to one’s sleep-wake type or times during the day when one naturally tends to be awake and asleep. A ‘night owl’ chronotype is said to have a later sleep-wake cycle, compared to an ‘early bird’ or a ‘lark’.
“Are you an early bird or a night owl? It’s hard to adjust what your biological clock – your so-called chronotype – is, but you can adjust your life to it as best you can,” study author Ana Wenzler, from the University Medical Center Groningen, the Netherlands, said.
Analysing the performance of about 23,800 participants on a cognitive test over a period of 10 years, the study found that ‘evening’ people decline cognitively faster than ‘morning’ people. The findings have been published in the Journal of Prevention of Alzheimer’s Disease.
“Unhealthy behaviour such as smoking, drinking and unhealthy eating happens more often in the evening,” Wenzler said.
“In our study, we also saw this: evening people smoke and drink more often and exercise less. Twenty-five per cent of the risk of cognitive decline can be explained from our research by smoking and poor sleep,” she said.
A greater decline was seen in higher-educated people – a delay of an hour in the sleep-wake cycle corresponded to a decline of 0.8 in cognition per decade. Wenzler said the decline might be related to their disturbed sleep rhythm.
“They are often people who have to go back to work early in the morning and are likely to sleep too short, giving their brains too little rest,” she said.
The author explained that people’s biological clock can change with age.
“Children are morning people. That changes when you reach puberty, when you become an evening person. Around your 20s, that gradually shifts back towards morning people for most people. By the age of 40, most people are morning people again,” Wenzler said.
However, this is certainly not the case for everyone, which is probably why evening people deviate from the norm, according to Wenzler, who recommended working against one’s body “as little as possible”.
“’You can try to go to sleep earlier, but if your body is not yet producing melatonin (sleep hormone), it will not work,” she said.
Wenzler added that if people are forced to work against their natural rhythm, their brains may not get enough rest, increasing the risk of unhealthy habits. “It would help if evening types were given the option to start work later,” she said.