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Pfizer pushes for third shot clearance as Delta strain drives global outbreaks

Pfizer pushes for third shot clearance as Delta strain drives global outbreaks

WITH cases rising again in Europe and the United States because of the Delta variant, Pfizer and BioNTech announced on Thursday (8) that they would seek authorisation for a third dose of their Covid-19 vaccine to boost its efficacy.

Pfizer and BioNTech said they expect that a third dose will perform well against the Delta strain, and that they will be seeking authorization in the United States, Europe and other regions in coming weeks.


Delta is the most infectious strain of the virus since the start of the global pandemic in early 2020.

Originally detected in India months ago, it has quickly spread and today is accelerating outbreaks even in countries with high vaccination rates.

This led the World Health Organization to warn that the world was at a "perilous point" as the official global death toll passed four million.

Third shot raises antibody level

Initial data from an ongoing trial showed a third shot pushed antibody levels five to 10 times higher against the original coronavirus strain and the Beta variant, first found in South Africa, compared to the first two doses alone, according to a statement.

The companies said they expected similar results for Delta - but added they are also developing a Delta-specific vaccine against the strain.

US regulators said on Thursday (8) they were still studying the need for booster shots.

"Americans who have been fully vaccinated do not need a booster shot at this time," the Food and Drug Administration and US Centers for Disease Control and Prevention said in a joint statement.

"We are prepared for booster doses if and when the science demonstrates that they are needed."

WHO warning

In Africa, the WHO warned the worst was yet to come after the most disastrous week in its history of pandemics.

"The fast-moving third wave continues to gain speed and new ground," said Dr Matshidiso Moeti, the WHO's regional director for Africa.

Tunisian authorities said the country's health system has "collapsed" under the weight of the pandemic, describing the situation as "catastrophic."

The WHO said more than four million people have died from Covid-19, but cautioned that the figure was likely an underestimate.

The UN body's chief Tedros Adhanom Ghebreyesus warned rich countries against complacency, and warned that the world was at a "perilous" point.

Delta is spiralling daily infections even in places where vaccination drives have been robust.

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Pub hotel group beat luxury chains in UK guest satisfaction survey

Highlights

  • Coaching Inn Group scores 81 per cent customer satisfaction, beating Marriott and Hilton.
  • Wetherspoon Hotels named best value at £70 per night.
  • Britannia Hotels ranks bottom for 12th consecutive year with 44 per cent score.
A traditional pub hotel group has outperformed luxury international chains in the UK's largest guest satisfaction survey, while one major operator continues its decade-long streak at the bottom of the rankings.
The Coaching Inn Group, comprising 36 relaxed inn-style hotels in historic buildings across beauty spots and market towns, achieved the highest customer score of 81per cent among large chains in Which?'s annual hotel survey. The group earned five stars for customer service and accuracy of descriptions, with guests praising its "lovely locations and excellent food and service.
"The survey, conducted amongst 4,631 guests, asked respondents to rate their stays across eight categories including cleanliness, customer service, breakfast quality, bed comfort and value for money. At an average £128 per night, Coaching Inn demonstrated that mid-range pricing with consistent quality appeals to British travellers.
J D Wetherspoon Hotels claimed both the Which? Recommended Provider status (WRPs) and Great Value badge for the first time, offering rooms at just £70 per night while maintaining four-star ratings across most categories. Guests described their stays as "clean, comfortable and good value.
"Among boutique chains, Hotel Indigo scored 79 per cent with its neighbourhood-inspired design, while InterContinental achieved 80per cent despite charging over £300 per night, and the chain missed WRP status for this reason.

Budget brands decline

However, Premier Inn, long considered Britain's reliable budget choice, lost its recommended status this year. Despite maintaining comfortable beds, guests reported "standards were slipping" and prices "no longer budget levels" at an average £94 per night.

The survey's biggest disappointment remains Britannia Hotels, scoring just 44 per cent and one star for bedroom and bathroom quality. This marks twelve consecutive years at the bottom, with guests at properties like Folkestone's Grand Burstin calling it a total dive.

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