The UK's biggest COVID-19 vaccine project, currently being tested by the University of Oxford, has shown some promising results in a small study with monkeys.
Researchers involved with the ChAdOx1 nCoV-19 trials said the vaccine had shown signs of priming the rhesus macaque monkeys’ immune systems to fend off the deadly virus and showed no indications of adverse effects.
According to the study, which is yet to be peer-reviewed, a single vaccination dose was also effective in preventing damage to the lungs – organs that can be severely affected by the virus.
"A single vaccination with ChAdOx1 nCoV-19 induced a humoral and cellular immune response in rhesus macaques," the authors said.
"We observed a significantly reduced viral load in bronchoalveolar lavage fluid and respiratory tract tissue of vaccinated animals challenged with SARS-CoV-2 (COVID-19) compared with control animals, and no pneumonia was observed in vaccinated rhesus macaques," they said.
The researchers found that after being exposed to high levels of the novel coronavirus, none of the six monkeys that were given the vaccine developed viral pneumonia. Also, there was no sign that the vaccine had made the animals more vulnerable.
The development has been welcomed as encouraging signs for a vaccine currently undergoing human trials but experts warn that it remains to be seen if it is as effective in humans.
"These results support the ongoing clinical trial of the vaccine in humans, the results of which are eagerly awaited," said Dr Penny Ward, visiting professor in pharmaceutical medicine at King''s College London.
Sarah Gilbert, professor of vaccinology at the University of Oxford's Jenner Institute who is leading the research, has previously said she has a "high degree of confidence" in the vaccine.
"Of course, we have to test it and get data from humans. We have to demonstrate it actually works and stops people getting infected with coronavirus before using the vaccine in the wider population," she said.
British drugs giant AstraZeneca has struck up a "landmark partnership" with the Oxford University team and said that 100 million doses could be made by the end of the year if the trials prove successful.
"We’re now starting to wait for an advocacy signal to see whether people who’ve been vaccinated don’t get the disease, so that’s the next step," said John Bell, professor of medicine at the University of Oxford.
However, the team is faced with the risk that there may not be enough active disease in the community for the participants to catch it naturally, calculations around which remain ongoing as the human trials progress in regions of the UK.
If the trial is successful in the UK, the Oxford team will approach scientists in the Kenya Medical Research Institute (KEMRI) and will approach the government of Kenya for permission to evaluate in Kenya.
"We also want to make sure that the rest of the world will be ready to make this vaccine at scale so that it gets to populations in developing countries, for example, where the need is very great," Bell said.
Meanwhile, it is hoped that results from the first human trials could be available by next month after healthcare workers on the frontlines of the pandemic were among those in the first batch of the trials in the UK.
The UK is the third worst-hit country in the world with 234,441 coronavirus cases. The US tops the chart with 1,417,889 cases, followed by Russia at 252,245.
The deadly virus has so far claimed 33,693 lives in the UK.
Top discounts on tech, beauty, home and essentials
Must-have offers include deals on Dyson, Nespresso, Oral-B, and more
Exclusive to Amazon Prime members (free trial available)
Amazon Prime Day 2025 is well underway, with this year’s event extended to a full 96 hours running from Tuesday 8 July to Friday 11 July. With thousands of products on offer across nearly every category, shoppers in the UK can enjoy steep discounts on everyday essentials, big-ticket tech, and top-rated beauty favourites.
We’ve sifted through the extensive listings to highlight 15 of the best value-for-money deals currently live, with savings of up to 60%. All prices are correct at the time of writing and exclusive to Prime members.
Save £81 Cordless, lightweight, and powerful, the Dyson V8 is one of the most sought-after vacuum models — and rarely goes on sale. Ideal for daily cleaning without the fuss of cords.
Save £20 The latest Kindle is Amazon’s lightest and most compact yet. With a high-resolution display and up to six weeks of battery life, it's a great entry point into e-readers.
Save £100 Includes a Vertuo Pop machine, milk frother, mugs, spoons and coffee pods. Excellent value for anyone looking to elevate their morning routine.
4. Samsung 50" Q60D QLED 4K TV – £325 (was £600)
Save £275 This 50-inch 4K QLED TV from Samsung is a solid choice for anyone seeking vivid visuals and reliable performance at nearly half the usual price.
5. Tefal Easy Fry Dual Zone digital air fryer – £131 (was £180)
Save £49 Featuring two drawers, multiple pre-set cooking options and a sync mode, this air fryer is well-reviewed for ease of use and excellent results.
6. Oral-B Pro 3 electric toothbrush – £62 (was £100)
Save £38 Recommended by hygienists and rated by shoppers, the Pro 3 offers up to 100% more plaque removal versus a manual toothbrush.
7. Olay Total Effects face cream set – £11.38 (was £24)
Save £12.62 Includes day and night creams suitable for all skin types. This tried-and-tested set is one of the best beauty buys under £15.
8. Shark FlexBreeze tableMate cordless fan – £89.99 (was £149.99)
Save £60 Perfect for summer, this quiet, portable fan comes with a 20-metre reach, five-speed settings, and a remote. Works indoors or outdoors.
9. Sony wireless noise cancelling headphones – £71 (was £99)
Save £28 Comfortable and feature-rich, these over-ear headphones deliver solid performance without breaking the bank.
Save £80 A high-capacity air fryer with two drawers, ideal for families or batch cooking. Philips’ Rapid Air Technology ensures even frying with less oil.
11. Narwey underseat cabin bag – £9.99 (was £15.99)
Save £6 A travel essential designed to fit under most airline seats. Comes in 14 colours and helps avoid costly baggage fees.
Save £27.68 A household staple — now better value than ever. The bulk pack should last months and saves over 50%.
15. Apple AirPods Pro 2 – £179 (was £229)
Save £50 If you’ve been eyeing Apple’s high-end earbuds, now’s a rare chance to get them discounted. Includes noise cancellation and spatial audio.
Tips to make the most of Prime Day:
Prime membership is essential – If you’re not yet a member, Amazon offers a 30-day free trial. After that, it’s £8.99/month.
Compare prices before checkout – Not all “deals” are as generous as they seem. Use tools like CamelCamelCamel to check historical prices.
Act fast – Some items, especially big tech or beauty discounts, may sell out quickly or go out of stock before Friday.
Whether you’re upgrading your kitchen appliances, refreshing your skincare shelf or just looking for practical home savings, Prime Day 2025 has something for nearly every shopper. But act quickly – the best offers won’t stick around long.
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Discover hidden UK beaches with turquoise waters and golden sands
Ideal for summer staycations without the cost of long-haul travel
Includes lesser-known spots in Wales, Scotland, Cornwall, and more
Perfect for quiet escapes, coastal walks, and Instagram-worthy views
Escape to paradise – no passport required
Think you need to fly halfway across the world for clear blue water and white sand? Think again. The UK is home to a surprising number of secluded beaches that look straight out of the Caribbean – without the crowds or jet lag. From hidden coves in Cornwall to windswept bays in the Scottish Highlands, here are some of the most tropical-looking beaches on British soil.
1. Barafundle Bay, Pembrokeshire, Wales
Often dubbed the UK’s answer to the Caribbean, this National Trust-owned gem boasts golden sand, crystal-clear waters, and dramatic cliffs. Accessed by a half-mile walk from Stackpole Quay, it remains blissfully untouched by development.
Best for: Picnics, photography, and a peaceful swim Nearest parking: Stackpole Quay car park
2. Achmelvich Bay, Sutherland, Scotland
Many of these beaches are tidal and best enjoyed at low tideiStock
With white sands and dazzling turquoise water, this beach in the remote northwest Highlands rivals beaches anywhere in the world. The journey is long, but the views – and near-solitude – make it worth every mile.
Tucked beneath rugged cliffs near Porthcurno, this tidal beach is often reached via a steep cliff path – but rewards visitors with stunning sandbars and glassy water at low tide. It’s also unofficially clothing-optional.
Best for: Adventurous walkers, secluded sunbathing Access: Steep footpath from Treen
4. Luskentyre Beach, Isle of Harris, Outer Hebrides
Framed by the turquoise seaiStock
Arguably one of Britain’s most spectacular beaches, Luskentyre’s vast white sands stretch for miles, framed by the turquoise sea and Harris’s dramatic hills. When the sun shines, it’s hard to believe you’re still in Scotland.
Best for: Landscape lovers, long coastal walks How to get there: Ferry from Skye to Tarbert, then a 25-minute drive
5. Kynance Cove, Cornwall
It’s best visited early or late in the dayiStock
With its striking serpentine rock formations, teal-coloured waters, and hidden caves, Kynance is a postcard-perfect Cornish cove. Its popularity means it’s best visited early or late in the day.
Best for: Exploring caves, paddling Nearby: Kynance Cove Café (seasonal)
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The chain had also gained a following for its themed brunches
Chinese dim sum restaurant Ping Pong has closed all its UK locations
The chain made the announcement via social media
Founded in 2005, the brand thanked customers and staff for their support
Loyal diners shared memories and disappointment in the comments
All branches are permanently closed
Chinese restaurant chain Ping Pong has permanently closed all its branches in the UK, the company confirmed in a social media announcement.
Founded in 2005 by restaurateur Kurt Zdesar, the dim sum chain had become popular for its stylish interiors, creative menus, and Asian-inspired cocktails. The company did not provide prior notice of the closure but said the decision marked the end of an “unforgettable” 20-year journey.
Social media announcement thanks customers and staff
In a post shared on Instagram, the company wrote: “It’s a wrap. After 20 unforgettable years, all Ping Pong locations are now permanently closed.
“We’re incredibly proud of what we built, an independent hospitality brand full of creativity, flavour and soul.
“To everyone who joined us over the years, for dim sum dates, happy hours, bottomless brunches, and just-because catch-ups – thank you.
“You shared your moments with us, passed around little parcels of deliciousness, and helped make Ping Pong what it was.
“To our collaborators, suppliers, and the incredible team who kept the steam going, thank you. It’s been sum-thing truly special.”
Customers express sadness over sudden closure
Regular customers responded to the announcement with disappointment and nostalgia. Many expressed shock over the sudden news and the lack of notice.
One Instagram user commented: “Noooo, we’ve made some amazing memories there, birthdays, anniversaries, you name it. The food was always so amazing.”
Another said: “WHAT?? WE HAD NO CHANCE TO SAY GOODBYE! NO WARNING.”
Others fondly recalled the restaurant’s atmosphere and signature dishes, with one writing: “The food and the lychee cocktails will be sorely missed.”
Ping Pong had multiple locations across London and was known for its contemporary take on traditional Chinese dim sum. The chain had also gained a following for its themed brunches, casual dining experience, and cocktail offerings.
No further information has been shared regarding the reason behind the closure or whether the brand will return in a new format.
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Neurogenesis, the process by which new neurons form in the brain
New neurons continue forming in the brain’s hippocampus into old age
Study confirms presence of neural progenitor cells in adults
DNA carbon dating and single-nucleus RNA sequencing were used
Research shows variation in neuron production between individuals
Findings could aid treatments for neurodegenerative and psychiatric disorders
Human brain shows ongoing neuron formation into older age
A new study has confirmed that the human brain continues to produce new nerve cells well into late adulthood, challenging previous assumptions about age-related decline in neurogenesis. The findings, published in the journal Science, provide fresh insight into how adaptable the brain remains over a lifetime.
Neurogenesis, the process by which new neurons form in the brain, is known to occur in the hippocampus — a region involved in memory. While previous research has suggested that this process continues throughout life, there has been limited concrete evidence of the presence of neural progenitor cells in the adult brain.
Research confirms presence of progenitor cells
The study, conducted by researchers at the Karolinska Institutet in Sweden, confirms the existence of these progenitor cells — cells that develop into neurons — in the adult hippocampus. The team used DNA carbon dating to determine when the cells were formed. Brain tissue samples from people aged 0 to 78 were analysed, sourced from international biobanks.
“We have now been able to identify these cells of origin, which confirms that there is an ongoing formation of neurons in the hippocampus of the adult brain,” said Jonas Frisén, professor of stem cell research at the Karolinska Institutet, who led the study.
Advanced techniques reveal cell activity
To conduct the study, the researchers applied a method known as single-nucleus RNA sequencing, which allows scientists to analyse gene activity in individual cell nuclei. This was combined with machine learning to identify the different stages of neuron development, from stem cells to immature neurons.
The team identified all neural progenitor cell stages in early childhood samples. In adult samples, they located dividing progenitor cells using antibodies against the proliferation marker Ki67, alongside machine learning algorithms.
The results not only confirmed that adult neurogenesis takes place but also revealed that many of the dividing cells were in active developmental stages.
Significant variation between individuals
A notable finding from the study was the large variation in the presence of progenitor cells between individuals. While some adults had many such cells, others had very few. The researchers said this variability could have implications for understanding individual differences in brain ageing and cognitive resilience.
They also found that although the progenitor cells in humans were similar to those in animals such as mice, pigs, and monkeys, the active genes involved differed, suggesting some species-specific distinctions in brain development.
Implications for brain health and disease treatment
The findings provide valuable insight into how the human brain changes over time and could have medical implications. As many neurodegenerative diseases, such as Alzheimer’s, involve the loss of neurons in regions like the hippocampus, understanding how new neurons form could contribute to the development of regenerative therapies.
“This is an important piece of the puzzle in understanding how the human brain works and changes during life,” said Frisén. “It may also guide future treatment strategies for neurodegenerative and psychiatric conditions.”
PTI KRS KRS VN VN NNNN
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Sophie, Duchess of Edinburgh, who grew up in Brenchley
Day one of the Kent County Show begins at Detling Showground near Maidstone
The Duchess of Edinburgh visits the event for the first time in 16 years
Organisers expect up to 70,000 visitors over the weekend
Farming and rural life are at the centre of the three-day programme
Highlights include live camel racing, equine sports, livestock displays and more
Kent County Show opens with royal visit
The Kent County Show returned to Detling near Maidstone on Friday, marking the start of a major three-day celebration of farming, food, and rural living. The event opened with a special visit from the Duchess of Edinburgh, who is attending for the first time in 16 years.
Sophie, Duchess of Edinburgh, who grew up in Brenchley near Tunbridge Wells and serves as patron of the Association of Show and Agricultural Organisations (ASAO), met with farmers, equine exhibitors, and local businesses on her tour of the showground.
Spotlight on farming and rural life
Organised by the Kent County Agricultural Society, the show brings together people from across the county to highlight the importance of agriculture and rural industries. Chairman Matthew Cullen said there was a "real buzz in the air" and called the royal visit a “great achievement”.
“There’s lots on offer,” he said. “From the livestock section with all the animals, young farmers, equine sports and food halls. We’ve also got something a little unusual this year – live camel racing. It isn’t what you’d normally get to see.”
Mr Cullen added that the event offers an opportunity for farmers to network and for the public to better understand how food is produced. “We all know Kent as the Garden of England, so for the rural and farming sector, it's a proud moment to come together and show off to the general public.”
Boost in interest following farming TV series
According to Mr Cullen, the farming sector has seen a noticeable spike in public interest, partly due to the popularity of the Amazon Prime series Clarkson’s Farm. “It has brought farming to the forefront of people’s minds,” he said, noting a broader uptick in engagement at agricultural shows across the UK.
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Friday highlights at the showground
The opening day features a packed programme of events across multiple rings. Highlights include:
09:30 – Kent Youth Trials (Heritage Ring)
10:00 – Joseph’s Amazing Racing Pigs (Countryside Ring)
11:15 – Camel Racing (John D Wood & Co Astor Ring)
11:45 – Sheep Dog Display (Countryside Ring)
12:15 – Hypo Hounds Diabetic Assistance Dog Display (Countryside Ring)
13:15 – Heritage Parade (John D Wood & Co Astor Ring)
15:05 – British Novice Showjumping with 90cm Open (Standen Ring)
17:30 – Donkey In Hand Championship (Pam Nesfield Ring)
Performances from Rock Choir and various vehicle and dog displays are also scheduled throughout the day.
Visitor information and tickets
Attendance for the weekend is expected to range between 60,000 to 70,000 people, depending on the weather. Tickets are still available to book online or can be purchased at the gate.
Adult tickets: £22 (in advance)
Child tickets: £3 (in advance)
Under 5s: Free entry
The Kent County Show continues through the weekend with a wide range of attractions, from local produce to equestrian competitions and entertainment for all ages.