Scientists highlight limitations of BMI in assessing metabolic health

During ENDO 2023, the Endocrine Society's annual meeting in Chicago, Illinois, new data was presented indicating that body mass index (BMI) should not be relied upon as a sole indicator of metabolic health.

The study revealed that a significant portion of individuals in the US who have a normal BMI still experience obesity-related conditions.

The research emphasises the significance of considering factors such as body composition, including the percentage of fat, muscle, bone, and water, as well as the distribution of fat in different body regions, particularly the abdomen and thighs.

Understanding these factors is crucial for gaining a comprehensive understanding of the underlying drivers of cardio-metabolic diseases.

"We show that there are racial/ethnic differences in body fat, BMI, and body fat distribution which may provide evidence for future studies to further determine if these differences are possible drivers of the racial disparities seen in cardio-metabolic diseases," said Aayush Visaria, M.D., M.P.H., an internal medicine resident at the Rutgers Robert Wood Johnson Medical School in New Brunswick, N.J.

Visaria and colleagues identified non-pregnant U.S. adults aged 20-59 years from the 2011-2018 National Health and Nutrition Examination Survey (NHANES) with whole body DEXA scan data.

Their BMI was categorised by ethnicity (non-Asian: underweight<18.5, normal=18.5-24.9, overweight=25-29.9, obese>=30 kg/m2, Asian: <18.5, 18.5-22.9, 23-27.4, 27.5+).

The researchers estimated odds of obesity among adults as normal/overweight based on BMI or total body fat percentage (BF%) as >=25% in male and >=32% in female, by race (non-Hispanic White [NHW], non-Hispanic Black [NHB], Asian, Hispanic, and other).

They also estimated mean DEXA adiposity measures by race.

They found that nearly 36% had BMI>=30 (the traditional definition of obesity) but 74% had obesity per BF%.

Among normal BMI adults, 44% of non-Hispanic Whites, 27% of NHB, 49% of Hispanic, and 49% of Asians had obesity as per BF%.

Among normal BMI adults, the mean android-to-gynoid fat ratio was 0.84 for NHW, 0.85 for NHB, 0.89 for Hispanics, and 0.91 for Asians.

Nearly 3 in 4 young-to-middle-aged U.S. adults were considered to have obesity according to BF% from DEXA scans.

Asian Americans and Hispanics with seemingly normal BMI were more likely to have obesity, and more likely to have a greater proportion of abdominal fat than non-Hispanic Whites.

Non-Hispanic Blacks had significantly lower chances of obesity at normal/overweight BMI ranges, and a lower proportion of abdominal fat.

"We hope this research will add to the idea of weight-inclusive care and allow clinicians to 1) routinely use supplementary measures of body fat such as waist circumference or bioimpedance-based body fat measurements (e.g. smart scales) in addition to BMI, 2) engage in practices to prevent unconscious biases that may occur when caring for a patient with obese BMI, and 3) engage in clinical decision-making that is not solely dependent on a BMI calculation but rather an overall idea of body composition and body fat distribution," Visaria said.

(ANI)