Paul Sinha, known to viewers of ITV’s The Chase as “The Sinnerman,” has spoken candidly about his experience living with Parkinson’s disease. During an appearance on Loose Women on Thursday, 17 April, the comedian and quizzer reflected on his journey from diagnosis to managing the condition day to day.
Sinha, who was diagnosed with the progressive neurological disorder in 2019, revealed that his earliest symptoms were not what many would typically associate with Parkinson’s.
“Everyone thinks Parkinson’s means you shake,” he said. “But for me, it started with a stiff, painful right shoulder. I didn’t think much of it at first; I assumed it would just go away. But it didn’t.”
He explained that over a year, he underwent various treatments and investigations, including injections, X-rays, and scans, before eventually having surgery in January 2019. However, even after the operation, the issue remained unresolved.
The real turning point came a few months later, while he was performing at a comedy festival in New Zealand.
“I started to limp,” he recalled. “There was a growing sense of doom. I was in a taxi and decided to Google ‘Parkinson’s and frozen shoulder’—and I got the fright of my life.”
He said that while a frozen shoulder isn’t a particularly rare symptom, it’s not among the more common ones either. That moment in the taxi sparked a wave of anxiety and concern, but also prompted him to seek definitive answers.
“I’ve always tried to be the perfect patient,” Sinha said. “I never want a doctor to assume I know what’s going on. I go in with the mindset of someone who knows nothing, so nothing gets missed.”
Eventually, a visit to the neurologist confirmed what he had feared: he had Parkinson’s disease. While the diagnosis was difficult, he said there was also an odd sense of relief.
“I just didn’t want it to be motor neurone disease or something that would decline faster,” he admitted. “Parkinson’s gave me a name for what I had, and a bit of time to get on with things I might want to do—although I’ve never actually had a bucket list.”
Sinha did, however, tick off one dream destination. “I went to Brazil last year,” he said. “That was a big one for me.”
Despite the diagnosis, Sinha said there has been no major shift in his lifestyle. He feels fortunate that his work schedule is flexible and not tied to a conventional nine-to-five job.
“I plan my days around what I’m doing,” he said. “I make sure I’m rested in the afternoon so I can get an early night. It’s all about managing energy.”
He also shared how he adapts his daily routine to ensure he can continue doing the things he enjoys, especially quizzing.
“I do an online speed quiz every day at 6 pm. That’s a must for me. But I know I need to take my second tablet of the day about an hour before, so my responses are sharp.”
When asked whether he worried about the future progression of his condition, Sinha was honest.
“It’s always on my mind, especially because of the work I do. As I become more physically disabled, I can still do The Chase and stand-up comedy. But if cognitive decline sets in, those things become impossible.”
He also touched on some of the physical limitations he now faces. “I have to sit on the bed to put my trousers on,” he shared, adding with a smile: “I’m lucky to have a very devoted husband. Oliver makes sure I look hot when I’m on TV.”
The audience responded warmly to the comment, showing their appreciation for the couple’s supportive relationship.
Throughout the interview, Sinha’s message was one of resilience and realism. While Parkinson’s remains a major part of his life, it hasn’t stopped him from pursuing his passions or connecting with his audience, with wit, honesty, and a touch of humour.
A new highly transmissible Covid variant, known as ‘Nimbus’, is raising concerns among health experts as cases rise sharply in parts of Asia and begin to appear in the UK. Official data shows that the strain, which has been labelled N.B.1.8.1, could drive a summer wave of infections due to its increased contagiousness and potential to evade immunity from earlier vaccinations or infections.
Cases detected in the UK
According to the UK Health Security Agency (UKHSA), 13 confirmed cases of the variant have already been recorded in England, and 25 British samples have been submitted to international databases since the end of March. However, experts say these figures likely underestimate the true spread, given the current limited Covid testing regime compared to the height of the pandemic.
UKHSA data up to 1 June reveals that 6.1 per cent of those tested for Covid were positive—the highest weekly figure for 2025. This marks a 7 per cent increase from the previous week and a 97 per cent rise compared to early March.
Rapid international spread
Nimbus, which is a descendant of the Omicron family of variants, has been linked to a spike in cases in China, Singapore, and Hong Kong. Globally, it now accounts for around 10.7 per cent of Covid infections, up from just 2.5 per cent a month earlier, according to the World Health Organisation (WHO).
The WHO has designated the variant as a ‘variant under monitoring’, which means it is being tracked for its potential impact but is not currently classified as a variant of concern.
Scientists warn of summer spike
British scientists are now warning that the new strain could fuel a rise in cases over the summer months, particularly as people become more socially active during the warmer weather.
Professor Lawrence Young, a virologist at Warwick University, said: “We are very likely to see a spike of infections over the next couple of months, possibly by later this month or in July. But it’s difficult to predict the level of this infection wave.”
He explained that population immunity from previous vaccinations or infections is likely waning, and unlike flu, Covid continues to spread in hot and humid weather. Laboratory studies also suggest that Nimbus is more efficient at infecting human cells and may have enhanced abilities to evade the immune system.
No evidence of increased severity
Despite its contagiousness, there is currently no indication that Nimbus causes more severe illness or higher mortality rates than earlier strains. However, experts caution that vulnerable groups—such as the elderly, people in care homes, and those with weakened immune systems—remain at risk of serious illness.
Data from the Office for National Statistics indicates that Covid contributed to just over 300 deaths in England during May 2025.
Symptoms and vaccine protection
The symptoms of the Nimbus variant appear to be consistent with those of previous Covid strains. These include fatigue, fever, sore throat and muscle aches.
There is currently no suggestion that the variant causes different or more severe symptoms. Moreover, scientists believe that existing Covid vaccines, reformulated to tackle Omicron and its descendants, should still offer protection against Nimbus.
UKHSA data shows that people who received a Covid booster last spring were 45 per cent less likely to require hospital treatment compared to those who remained unvaccinated.
Who is eligible for the vaccine?
In the UK, free Covid vaccinations are currently being offered to:
Adults over the age of 75
Residents and staff in care homes
Individuals with weakened immune systems
The UKHSA has urged all eligible people to take up the vaccine offer to help protect themselves and others from severe illness, particularly with the rising presence of the Nimbus strain.
Officials closely monitoring situation
Dr Gayatri Amirthalingam, deputy director at UKHSA, confirmed that the agency is closely tracking the spread of the N.B.1.8.1 variant both domestically and internationally.
“UKHSA is monitoring all available data relating to SARS-CoV-2 variants in the UK and abroad, and we continue to publish our findings in our regular Flu and Covid-19 surveillance reports,” she said.
“NB.1.8.1 has been detected in small numbers in the UK to date, but international data suggests that it is growing as a proportion of all Covid-19 cases.”
As the summer approaches, experts are reminding the public that even though the pandemic is no longer dominating daily life, Covid continues to evolve. The emergence of Nimbus underscores the need for vigilance, particularly among those at higher risk.
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Ranganathan discussed experiencing suicidal thoughts in the past and the steps he has taken to improve his mental health
Comedian and presenter Romesh Ranganathan has opened up about his long-term mental health challenges, describing how he has found effective ways to manage his wellbeing and now feels he is in “one of the best places I’ve ever been in my life”.
Speaking on BBC Radio 4’s Desert Island Discs, Ranganathan discussed experiencing suicidal thoughts in the past and the steps he has taken to improve his mental health. He also reflected on his Sri Lankan heritage, his upbringing, and the difficulties his family faced during his youth.
Managing mental health with daily routines
Ranganathan said he uses running, reading and breathing exercises to help maintain his mental wellbeing. These habits have become an important part of his routine.
“One of the things I’ve noticed when it comes to mental health is you do stuff that works… and then for some reason you just stop doing it,” he said. “You go, ‘Oh, I’ve done that every day for a week, I’m really feeling better, shall I just stop? Yeah!’ And then a few weeks later, wonder why I feel much worse.”
He described recognising when his mental health dips as “half the battle”, explaining that he is now better equipped to respond to difficult periods. “Sometimes I just go through a dark period and I know that I’ve got to do something about it,” he said.
Sharing mental health experiences responsibly
The 47-year-old broadcaster also reflected on the challenges of discussing mental health publicly, particularly when such conversations might affect others.
“You’ve got to be careful because it’s triggering [for other people],” he told presenter Lauren Laverne. “The way that I try and tackle that is to talk about it… I’m trying to destigmatise it to make the conversation normal.”
Mental health should be something people feel able to talk about openlyBBC Radio 4
However, Ranganathan acknowledged the fine line involved in public disclosures. “You do also have to be mindful of the fact that people may have been affected by that,” he said. “You don’t always get it right, but I think the rewards outweigh the risks.”
He explained that, like physical illness, mental health should be something people feel able to talk about openly. But he also emphasised the importance of being sensitive to those who may have personal experiences with suicide or depression.
Personal losses and long-term challenges
Ranganathan revealed that his struggles with mental health date back to his teenage years. He recalled particularly difficult moments during his A-levels, when his father was imprisoned for fraud, and the wider financial difficulties the family faced at the time.
“I’ve been through in my life a number of periods of suicide ideation,” he said. Despite these challenges, he said he currently feels mentally strong and positive. “As I speak now, this is running close to one of the best places I’ve ever been in my life mentally.”
His father died in 2011, but Ranganathan continues to reflect on his parents' lives and the lasting impact they’ve had on him.
Honouring his mother’s strength
During the interview, Ranganathan spoke warmly about his mother, Shanthi, and described her as “one of my heroes”. He shared how his parents moved to the UK from Sri Lanka in 1970, eight years before he was born.
While his father embraced British culture, socialising and working, Ranganathan said his mother had a very different experience. “That’s a 19-year-old girl who had kids in a foreign country,” he said. “My dad was going off to work… my mum is at home and going to the shops, but… there’s a strong argument he should’ve implemented more boundaries than he did.”
He admitted that one of his biggest regrets is “not having enough empathy or understanding” of his mother’s situation when he was growing up.
Family challenges and early life
Ranganathan recalled a difficult period when he was 12, and his father lost his job and struggled financially. “He was trying to make money in his sort of Sri Lankan Del Boy way, and it wasn’t working out,” he said. “He couldn’t keep up the mortgage repayments on their house.”
His father was later arrested and sentenced to two years in prison for fraud, an event that deeply affected Ranganathan during his teenage years.
Despite these hardships, Ranganathan eventually found success in comedy in the early 2010s and has since become a household name in the UK. He now hosts a weekend show on BBC Radio 2 and has fronted numerous popular television programmes.
Music and reflections
As part of his Desert Island Discs appearance, Ranganathan selected songs from artists including Kanye West, Eminem, and Huey Lewis and the News. His musical choices reflected different stages of his life and emotional journey.
The interview provided a rare and honest glimpse into the comedian’s personal experiences and mental health journey, offering encouragement to others who may be facing similar struggles.
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Jessie J said she was choosing to focus on the fact it was caught early and expressed gratitude
Singer Jessie J has announced she was diagnosed with early-stage breast cancer in April, sharing the news with her fans via an emotional video posted to Instagram. The 37-year-old artist revealed that she had been undergoing medical tests for the past two months while continuing to perform and release music.
“I was diagnosed with early breast cancer,” said Jessie J, whose real name is Jessica Cornish. “Cancer sucks in any form, but I’m holding on to the word ‘early’.” The Price Tag singer explained that she had been “in and out of tests” since her diagnosis, while still managing her music career and public commitments.
Balancing health and career
Jessie J said the diagnosis came shortly before the release of her latest single, No Secrets. She is scheduled to perform at Capital’s Summertime Ball at Wembley Stadium on 15 June, after which she plans to undergo surgery.
“I am going to disappear for a bit after Summertime Ball to have my surgery,” she said. “And I will come back with massive tits and more music,” she added, using humour to manage what she described as a deeply challenging experience.
Despite the serious nature of the diagnosis, Jessie J said she was choosing to focus on the fact it was caught early and expressed gratitude that it had been identified in time for treatment.
Opening up about timing and emotions
She also reflected on the timing of the diagnosis, which coincided with the promotional rollout for songs including No Secrets and Living My Best Life. Both singles were prepared in advance of her diagnosis, making the coincidence especially poignant.
“To get diagnosed with this as I’m putting out a song called No Secrets right before a song called Living My Best Life… you can’t make it up,” she said.
Jessie J explained that she needed time to process the news, and decided to speak publicly as a way of confronting the reality of her illness and to reach out to others going through similar experiences. “I just wanted to be open and share it,” she said. “Selfishly, I do not talk about it enough. I’m not processing it because I’m working so hard.”
Support from fans and friends
After her announcement, fans and fellow celebrities expressed their support in large numbers. TV presenter Gaby Roslin commented, “Sending you so much love and enormous hugs,” while others offered similar messages of encouragement and solidarity.
One follower wrote, “God is already busy healing you. You give us so much kindness. It’s time for the universe to give back some of that light.” Another said, “You are not alone. May your recovery be gentle, peaceful, and full of healing. Sending you a tight hug and all the love my heart can carry.”
Jessie J later shared on her Instagram story that she was still emotionally processing the situation. “Honestly, I need to process it and talk about it. I need a hug,” she said.
Ongoing health struggles
This is not the first time Jessie J has had to face serious health issues. She was diagnosed with a heart condition at the age of eight and suffered a minor stroke at 18. In 2020, she experienced a brief period of hearing loss, and in 2021, she went through the trauma of a miscarriage.
The singer welcomed her first child, son Sky Safir Cornish Colman, in May 2023Getty Images
In May 2023, she gave birth to her first child, a son named Sky Safir Cornish Colman, with her partner Chanan Safir Colman, a retired Danish-Israeli basketball player. Sharing her journey as a new mother has formed part of her recent online updates, as she balances her personal life with her return to the stage.
Tour still planned
Despite her diagnosis and upcoming surgery, Jessie J has not postponed or cancelled her planned tour dates. The European and UK No Secrets Tour 2025 is still scheduled to begin later this summer, with the opening show set to take place in Amsterdam.
While there may be adjustments to her schedule in the coming months, the singer has indicated she remains committed to performing and sharing new music with fans.
Spreading awareness
By sharing her diagnosis, Jessie J has once again demonstrated her openness with fans and her willingness to use her platform to raise awareness. While she acknowledged that she has not always taken time to fully process her own experiences, she said that hearing from others going through similar struggles has helped her feel less alone.
“It breaks my heart that so many people are going through so much similar and worse—that’s the bit that kills me,” she said.
With her tour on the horizon and treatment ahead, Jessie J continues to face her health challenge with strength and honesty—qualities that have long defined her music and public persona.
As Men’s Health Week 2025 (9–16 June) approaches, UK-based charity Lepra is raising awareness of hydrocele, a largely overlooked condition that significantly impacts men’s lives. A complication of lymphatic filariasis (LF), hydrocele causes fluid to accumulate in the scrotum, resulting in extreme swelling that can hinder mobility, limit income opportunities, and affect personal relationships.
Despite the availability of a simple surgical fix, many men suffer in silence due to social stigma, lack of awareness, and barriers to treatment.
A personal struggle: Arjun’s story
Arjun, 38, lives in a rural village in Odisha, India, with his wife, four children and father. As the family's main provider, he worked as a labourer until, six years ago, he began experiencing swelling and pain in his scrotum. The condition gradually worsened, leaving him unable to work effectively. Arjun endured daily discomfort, emotional distress, and increasing isolation due to embarrassment about his condition.
Post-surgery, Arjun experienced a significant improvement in his physical healthLepra
His family, unaware of the cause, worried about the financial burden of treatment. The turning point came when Arjun was screened by a Lepra programme and diagnosed with hydrocele.
Understanding hydrocele and its causes
Hydrocele is a common long-term effect of lymphatic filariasis, a neglected tropical disease transmitted by mosquitoes, usually during childhood. According to the World Health Organization (WHO), LF often remains asymptomatic for years while silently damaging the lymphatic system. As men age, this damage can manifest as chronic conditions, including lymphoedema, elephantiasis, and hydrocele.
Hydrocele can cause significant pain and immobility. Married men may struggle with intimacy, while single men often face social exclusion. In many cases, the stigma surrounding the condition leads to isolation, low self-esteem, and mental health challenges.
The simple solution: Hydrocelectomy
Hydrocele can be completely cured through hydrocelectomy, a straightforward surgical procedure with a recovery period of just two weeks. Yet access to this surgery is limited in many areas due to a shortage of trained surgeons and the stigma that prevents men from seeking help.
Following his diagnosis, Arjun received counselling to help him cope with the emotional toll of his condition. Although initially hesitant, he agreed to undergo surgery. After the operation, Arjun’s physical health improved dramatically. He regained the ability to work, restored his independence, and began reintegrating into his community.
The wider problem: Underreported and undertreated
It is estimated that up to half of men who contract LF in childhood will develop hydrocele in adulthood. In 2023 alone, WHO recorded a 258,886 increase in reported hydrocele cases globally, while only 7,380 surgeries were carried out, a stark reminder of the treatment gap.
Although hydrocelectomies are available for free in public hospitals, long waiting lists and inadequate surgical capacity prevent many from accessing timely care. In response, Lepra arranges private surgeries at a cost of just £100 for men unable to wait or travel for public treatment.
Lepra’s ongoing efforts
Lepra not only facilitates surgery but also works with local governments in India and Bangladesh to expand training for hydrocelectomy and improve access to care. The charity also runs community support groups led by trained volunteers who play a crucial role in awareness campaigns and pre-screening education.
These networks help break down stigma by informing communities about LF and the importance of early diagnosis. They also address common fears around surgery and travel, encouraging more men to come forward before the condition worsens.
About lymphatic filariasis
Lymphatic filariasis is classified by the WHO as a neglected tropical disease. It is caused by filarial parasites transmitted through mosquito bites. While infection usually begins in childhood, the consequences can appear much later, affecting the lymphatic system, kidneys, and immune response. Chronic conditions linked to LF include lymphoedema, elephantiasis, and hydrocele.
About Lepra
Lepra, originally founded in 1924 as the British Empire Leprosy Relief Association (BELRA), has been known simply as Lepra since 2008. The organisation works in India and Bangladesh, diagnosing and treating people affected by leprosy and related neglected diseases. Alongside medical care, Lepra tackles prejudice and discrimination through education, rehabilitation, and advocacy.
The charity operates under the patronage of His Majesty King Charles III and has His Royal Highness The Duke of Gloucester KG GCVO as Vice President.
To find out more or support Lepra’s work, visit:www.lepra.org.uk
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Participants were led to believe that 184 strangers would review a personal profile they had submitted
A new study has found that testosterone may heighten men’s sensitivity to social feedback, influencing how they perceive themselves in response to approval or disapproval. Published in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, the research suggests that testosterone does not simply boost or diminish self-esteem, but changes how strongly social feedback affects an individual's sense of self-worth.
The study focuses on what psychologists call "state self-esteem," a temporary, fluctuating sense of self-worth that responds to social interactions. This is different from "trait self-esteem," which reflects a person’s more stable, long-term self-assessment. Fluctuations in state self-esteem can have significant consequences, including links to anxiety, depression, and aggression. The findings could also help explain why men with lower self-esteem might be more vulnerable to mood disorders or antisocial behaviour.
Fluctuations in state self-esteem can have significant consequencesiStock
Researchers from several institutions, including the University of Electronic Science and Technology of China and the University of Zurich, carried out the double-blind, placebo-controlled study. They recruited 120 healthy men aged 18 to 26, who were randomly assigned to receive either a testosterone gel or a placebo. After applying the gel, participants waited three hours for hormone levels to rise before taking part in a social evaluation task.
Participants were led to believe that 184 strangers would review a personal profile they had submitted and then respond with either approval (thumbs-up), disapproval (thumbs-down), or no feedback. In reality, the feedback was pre-programmed. Participants predicted how likely each rater was to approve of them and, after each round, rated how they felt about themselves, providing a real-time measure of state self-esteem.
The results showed that testosterone influenced how men formed expectations of social feedback. Those who received testosterone were more optimistic when anticipating approval from positively biased raters but more pessimistic when faced with likely disapproval. In essence, testosterone sharpened their social radar, increasing sensitivity to both praise and criticism.
More notably, testosterone amplified the emotional effects of feedback. Positive feedback led to greater boosts in self-esteem, while negative feedback caused more pronounced declines, compared to the placebo group. These patterns were assessed using computational modelling that treated self-esteem changes as a learning process, based on feedback and prediction errors.
The model revealed that testosterone did not affect the basic rate at which participants updated their self-esteem but did increase the emotional weight given to feedback. In particular, it amplified attention to both expectations and the discrepancies between expected and actual outcomes. This suggests that testosterone enhances the brain’s responsiveness to social cues, intensifying the emotional highs and lows associated with acceptance and rejection.
The findings support the idea that self-esteem functions as a “sociometer,” reflecting how accepted or rejected a person feels in their social environment. Testosterone appears to tune this sociometer, making men more emotionally responsive to social evaluations.
Men with low self-esteem are more susceptible to mental health issuesiStock
These insights could have practical implications. For instance, men with low self-esteem are more susceptible to mental health issues, and testosterone therapy is sometimes used to alleviate mood symptoms. Combining hormone treatments with positive social environments or therapies that offer regular, affirming feedback might be more effective in supporting mental well-being.
However, the study had limitations. All participants were young men, so it is unclear whether similar effects would be observed in women or in older individuals. Moreover, the researchers did not measure participants' baseline testosterone levels, which could influence how individuals respond to hormonal changes.
Another limitation lies in the study's design. Although the social evaluation task aimed to replicate real-life interactions, participants were aware they were part of an experiment, which might have affected their responses. Still, the controlled setting allowed researchers to isolate and measure the psychological processes involved.
Social evaluation task aimed to replicate real-life interactionsiStock
Future research could explore how testosterone affects social learning and self-esteem in more naturalistic settings or in clinical populations, such as those with social anxiety or depression. Additional studies could also investigate the role of other hormones and types of feedback, such as comments from peers or authority figures.
The study, titled "Testosterone Administration Increases the Computational Impact of Social Evaluation on the Updating of State Self-Esteem," was authored by Jixin Long, Junsong Lu, Yang Hu, Philippe N. Tobler, and Yin Wu. It highlights the complex role testosterone plays in shaping self-esteem and emotional sensitivity, opening new paths for understanding the hormonal underpinnings of mental health.