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Mixed AstraZeneca-Pfizer shot boosts Covid antibody level, says study

Mixed AstraZeneca-Pfizer shot boosts Covid antibody level, says study

A mixed vaccination of first AstraZeneca and then a Pfizer Covid-19 shot boosted neutralising antibody levels by six times compared with two AstraZeneca doses, a study from South Korea showed.

The study involved 499 medical workers - 100 receiving mixed doses, 200 taking two doses of the Pfizer/BioNTech shot and the remainder getting two AstraZeneca shots.


All showed neutralising antibodies, which prevent the virus from entering cells and replicating, and the result of the mixed schedule of vaccines showed similar amounts of neutralising antibodies found from the group that received two Pfizer shots.

A British study last month showed similar results - an AstraZeneca shot followed by Pfizer produced the best T-cell responses, and a higher antibody response than Pfizer followed by AstraZeneca.

The data provides further support for the decision of several countries to offer alternatives to AstraZeneca as a second shot after the vaccine was linked to rare blood clots.

The South Korean study also analysed neutralising activity against major variants of concern, the Korea Disease Control and Prevention Agency (KDCA) said.

None of the groups demonstrated reduced neutralising activity against the Alpha variant, first identified in Britain, but the neutralisation titre decreased by 2.5 to 6 fold against Beta, Gamma and Delta, first detected in South Africa, Brazil and India respectively.

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Starmer and Glastonbury condemn anti-Israel chants by Bob Vylan

Keir Starmer speaks to members of the media during a visit to RAF Valley, on Anglesey in north-west Wales, on June 27, 2025. PAUL CURRIE/Pool via REUTERS

Starmer and Glastonbury condemn anti-Israel chants by Bob Vylan

PRIME MINISTER Keir Starmer and Glastonbury organisers said on Sunday (29) they were appalled by on-stage chanting against the Israeli military during a performance at the festival by Punk-rap duo Bob Vylan.

During their show on Saturday (28), the duo chanted "Death, death, to the IDF" in reference to the Israel Defense Forces, the formal name of the Israeli military.

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A flooded street near Station Road after heavy rainfall in Hyderabad, Pakistan, on June 27, 2025.

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Pakistan reports 45 deaths from flash floods and rain in monsoon onset

AT LEAST 45 people have died in Pakistan over the past few days due to flash flooding and heavy rainfall since the beginning of the monsoon season, according to disaster management officials on Sunday.

The highest number of deaths was reported in Khyber Pakhtunkhwa province, which borders Afghanistan. There, 21 people were killed, including 10 children.

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UK Weather Alert: June Heatwave to Hit 34°C, Breaking Records

The UK is bracing for potentially one of the hottest June days on record

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UK set for one of the hottest June days with highs of 34°C

Key points

  • Temperatures may hit 34°C in Greater London and Bedfordshire
  • Amber alert in place across five regions due to health risks
  • Wimbledon’s opening day to be hottest on record
  • Risk of wildfires in London labelled “severe”
  • Scotland and Northern Ireland remain cooler

Hottest June day in years expected as second UK heatwave peaks

The UK is bracing for potentially one of the hottest June days on record, with temperatures expected to reach 34°C on Monday (30 June). The ongoing heatwave, now in its fourth day, is most intense across the South and East of England, particularly in Greater London and Bedfordshire.

Although there is a small chance of temperatures hitting 35°C, they are unlikely to surpass the all-time June record of 35.6°C set in 1976.

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Air India flight crash
Air India's Boeing 787-8 aircraft, operating flight AI-171 to London Gatwick, crashed into a medical hostel complex shortly after take-off from Ahmedabad on June 12.
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Probing all angles in Air India crash, including sabotage: Minister

INDIA’s junior civil aviation minister said on Sunday that all possible angles, including sabotage, were being looked into as part of the investigation into the Air India crash.

All but one of the 242 people on board the Boeing 787-8 Dreamliner were killed when it crashed in Ahmedabad on June 12. Authorities have identified 19 others who died on the ground. However, a police source told AFP after the crash that the death toll on the ground was 38.

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Police may probe anti-Israel comments at Glastonbury

Moglai Bap and Mo Chara of Kneecap perform at Glastonbury Festival at Worthy Farm in Pilton, Somerset, Britain, June 28, 2025. REUTERS/Jaimi Joy

Police may probe anti-Israel comments at Glastonbury

BRITISH police said they were considering whether to launch an investigation after performers at Glastonbury Festival made anti-Israel comments during their shows.

"We are aware of the comments made by acts on the West Holts Stage at Glastonbury Festival this afternoon," Avon and Somerset Police, in western England, said on X late on Saturday (28).

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