Highlights
- Kris Jenner said she stopped using Ozempic after experiencing severe nausea
- Jenner described peptide injections and supplements as a “game changer” for her energy levels and wellbeing
- Interest in peptide-based wellness treatments continues to grow despite concerns around regulation and safety
Kris Jenner opens up about why Ozempic did not work for her
Kris Jenner has revealed she stopped using Ozempic after the medication left her feeling too unwell to continue.
Speaking on the SHE MD Podcast, Jenner discussed her experience with GLP-1 drugs while appearing alongside gynaecologist Dr Thais Aliabadi and women’s advocate Mary Alice Haney.
According to Jenner, she tried Ozempic before the drug became widely recognised in popular culture, but quickly realised it was not suitable for her.
“I tried it once when no one knew what it was, and it made me really sick,” Jenner said during the podcast.
She explained that the nausea became so intense it affected her ability to work and carry out daily routines.
Peptide injections became her alternative
After stopping Ozempic, Jenner said she and her doctor explored other treatment options before settling on peptide injections combined with supplements including omega-3s.
She described the new routine as a “game changer”, particularly because it improved her energy levels during long workdays.
Jenner said the treatment gave her “an extra couple of hours” at night, explaining that she often begins work early and usually feels exhausted by the end of the day.
She also claimed the supplements had visible benefits for her hair, skin and nails in addition to helping her feel more energised overall.
Growing interest in peptide treatments continues
Jenner’s comments arrive at a time when peptide-based wellness treatments are attracting increasing attention across the beauty, health and fitness industries.
According to the American Medical Association, peptide injectables are now being used not only for weight loss but also for muscle recovery, anti-ageing treatments and metabolic health.
Ozempic itself is a peptide-based medication that has undergone far more clinical research than many newer injectables now appearing in wellness clinics and online markets.
Some peptide treatments are also prescribed for diabetes management and blood sugar control, with insulin among the best-known examples.
However, medical experts have also raised concerns about the growing number of peptide products being promoted without full regulatory approval. Many newer injectables remain outside formal approval systems and are increasingly being sold through loosely regulated wellness spaces.
Health professionals continue to advise that any peptide-based treatment should only be taken under medical supervision.













