• Friday, March 29, 2024

Coronavirus

UK launches studies worth over £4mn on link between Covid-19 impact and ethnicity

In response to the projects, Professor Chris Whitty, chief medical officer for England and head of the NIHR said it was “critical” to understand why BAME groups were more severely affected by coronavirus. (Photo: JUSTIN TALLIS/AFP via Getty Images)

By: Eastern Eye Staff

THE link between the coronavirus pandemic and ethnicity will be investigated in six new multi-million pound research projects, it was announced on Wednesday (29).

Funded by UK Research and Innovation (UKRI) and the National Institute for Health Research (NIHR), the projects will seek to explain and mitigate the disproportionate death rate from Covid-19 among people of Black, Asian and minority ethnic (BAME) backgrounds.

The announcement follows statistics which showed ethnic minorities are nearly twice more likely to die from the deadly virus than white people. A recent Public Health England (PHE) report revealed 63 per cent of healthcare workers who died from Covid-19 were from a BAME background.

In response to the projects, Professor Chris Whitty, chief medical officer for England and head of the NIHR said it was “critical” to understand why BAME groups were more severely affected by coronavirus.

“The diverse range of projects funded by the NIHR and UKRI will help examine this association in detail, so that new treatments and approaches to care can be developed to target the ethnicities most at risk,” he explained. “This research will have embedded patient and public involvement with Black, Asian and minority ethnic groups at all stages of the research.”

The project, totalling £4.3 million worth of funding, will explore the impact of the virus specifically on migrant and refugee groups. According to UKRI, the group of projects forms “part of a rolling call” for research proposals on Covid-19 and will include research on treatments, vaccines and the spread of the virus, as well as specific calls on Covid-19 and ethnicity, and the wider impact of the virus on mental health.

It will aim to work with key voices within ethnic minority communities to create targeted, digital health messages, organisers said. UKRI and NIHR have additionally promised to introduce a new framework to ensure the representation of people from BAME backgrounds in clinical trials testing new treatments and vaccines for Covid-19.

Kemi Badenoch MP, exchequer secretary to the Treasury, said the research was “testament” to how seriously the government was handling the issue.

“It is critical that citizens, whatever their background, are appropriately supported in the fight against Covid 19,” she said. “This includes researching the impact of the virus on them. It is vital that all the action we take is evidence-based and fully informed.

“This multimillion pound investment will enable our scientists and health workers to investigate further and get the information needed to protect the lives of our citizens.”

Dr Manish Pareek, principal investigator of the UK-REACH study, University of Leicester and honorary consultant at University Hospitals of Leicester NHS Trust, is one of the researchers to receive funding from the scheme. The ‘UK Research Study into Ethnicity And Covid-19 outcomes in Healthcare workers (UK-REACH)’ will calculate the risk of contracting and dying from Covid-19 for ethnic minority healthcare workers, with access to over two million healthcare records held by national healthcare organisations.

“Our study is the first to be conducted on a large scale, investigating why BAME healthcare workers could be at greater risk,” the academic explained. “We want this research to improve the lives of healthcare staff – to this end, we have a stakeholder group of major national organisations to research and publicise our findings.”

 

THE PROJECTS

Dr Manish Pareek, University of Leicester and Honorary Consultant at University Hospitals of Leicester NHS Trust – £2.1m

UK-REACH will calculate the risk of contracting and dying from Covid-19 for ethnic minority healthcare workers. It will follow a group of healthcare workers from BAME backgrounds over 12 months to track changes in their physical and mental health. Working with the General Medical Council, the Nursing and Midwifery Council, General Dental Council, NHS Employers and BAME Professionals’ Associations, evidence will be provided to policymakers so that decisions can be made in near real-time.

Dr Robert Aldridge, UCL – £1.4 million

This project aims to better understand the impact of Covid-19 on minority ethnic and migrant groups and how to tackle it in community settings. They will study household transmission, occupation, co-morbidities, healthcare usage, and mental health and economic impacts. In collaboration with Public Health England, they will determine how often these groups are diagnosed, hospitalised and die with Covid-19 and how this is affected by their socioeconomic situation and pre-existing health conditions.

Professor Aftab Ala, Royal Surrey NHS Foundation Trust and Kings College Hospital, Honorary Professor at the University of Surrey – £371k

This project aims to design culturally relevant health messages for Black and South Asian groups and deliver these messages through specific and trusted communications channels, to influence behaviours that reduce the transmission of Covid-19.

Professor Julia Hippisley-Cox at the University of Oxford and Dr Hajira Dambha-Miller at the University of Southampton – £327k

This study will determine the risk of infection and death from Covid-19 in individual ethnicity groups and seek to explain why these differences might exist. The team will combine over 40 million patient GP records across rural and urban areas of England to create one of the largest Covid-19 cohorts in the UK.

Professor Thomas Yates, University of Leicester – £126k

This study will use the UK Biobank cohort, which has been linked to national Covid-19 data. This work will start to unpick why minority ethnic groups may be at increased risk and whether this increased risk is observed equally across the population.

Professor Shaun Treweek, University of Aberdeen – £15k

This project will see the rapid completion of a tool called the INCLUDE Ethnicity Framework, enabling the designers of clinical trials to consider the factors that may reduce the inclusion of BAME participants, such as existing disease, culture, treatment being tested, and trial information and procedures. The framework will be applied to three to five trials, including Covid-19, to produce an example set for other trialists to use when planning future Covid-19 trials.

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