Canadian singer, Celine Dion has revealed she is suffering from Stiff Person Syndrome, a rare incurable neurological disorder. The 54-year-old took to Instagram to disclose her medical condition that is responsible for uncontrollable muscle spasms.
She has announced that the diagnosis means that she will cancel or postpone dozens of shows in her “Courage World Tour” from spring 2023 to 2024 and the cancellation of 8 shows that is scheduled for summer 2023, The Times of India reports.
In an emotional, Instagram video, Dion, reportedly told her fans, “I’ve been dealing with problems with my health for a long time, and it’s been really difficult for me to face these challenges and to talk about everything that I’ve been going through.”
The caption of her video she posted on Instagram reads, “I am deeply saddened to say that I will not be ready to resume my Europe tour in February."
In her statement, Dion also said that the muscle spasms have made her life difficult.
She reportedly said, “Unfortunately, these spasms affect every aspect of my daily life, sometimes causing difficulties when I walk and not allowing me to use my vocal cords to sing the way I’m used to.”
What is Stiff Person Syndrome or SPS?
According to Johns Hopkins Medicine, SPS is a rare neurological disorder that affects one or two in a million people. The disease causes progressive muscle stiffness and intense spasms.
The muscle stiffness and muscle spasms are experienced in the trunk and limbs, and affects posture, balance, and the ability to use certain muscles.
The National Institute of Neurological Disorders and Stroke (NINDS) which supports research related to SPS informs that it is a "neurological disorder with features of an autoimmune disease."
Symptoms
NINDS states that the symptoms may include stiff muscles in the trunk (torso), arms, and legs. There is reportedly also greater sensitivity to noise, touch, and emotional distress, which can trigger muscle spasms.
Over time, those with SPS may develop abnormal, often hunched over postures. Additionally, some people may be too disabled to walk or move.
Speaking about SPS Dr Kunal Desai, a Yale Medicine neurologist and assistant professor of neurology who specializes in neuromuscular disease, told USA TODAY, "It's a disease that's characterized by progressive muscle stiffness, muscle spasms, rigidity – typically in the muscles of the back, specifically the lower back, as well as the upper legs."
He said, "It can affect other muscles, including muscles in the arms as well as speaking and swallowing muscles, but that's less common."
Yale Medicine informs that it’s possible for the muscle spasms to be "so severe that they cause the person to fall down.”
Experts state people with SPS tend to fall down because they lack the normal reflexes to catch themselves.
Dr Robert Wilson, a neurologist and the director of the Autonomic Center at the Cleveland Clinic is quoted as saying, "We all have muscle spasms, but these are muscle spasms that are beyond your control to the point that muscles lock and are so rigid. There's truncal dystonia."
Truncal dystonia can be described as a neurological movement disorder characterised by involuntary muscle contractions.
Regarding some severe cases he's seen, Dr Robert adds, "The limb can look distorted and contorted. I've seen people actually break a limb from it."
Why SPS is a rare condition
Though scientists don’t yet understand what causes SPS, research indicates that this condition is triggered as a result of an autoimmune response gone awry in the brain and spinal cord.
According to information provided by the NINDS, SPS is often misdiagnosed as Parkinson’s disease, multiple sclerosis, fibromyalgia, psychosomatic illness, or anxiety and phobia.
Diagnosis
Since the disease is so rare, diagnosing the syndrome is supposedly difficult. The NINDS website informs that a definitive diagnosis can be made with a blood test. This test can be conducted to measure the level of glutamic acid decarboxylase (GAD) antibodies.
Most people with SPS have reportedly elevated levels of GAD antibodies.
Additionally, a report in USA TODAY mentions that the diagnosis can also be confirmed with the following:
• A comprehensive review of a patient's medical history.
• A neurological exam and tests including blood tests, spinal fluid analysis.
• An Electromyography (EMG) to assess the health of muscles and nerve cells that control them.
Treatment
Experts believe that though SPS is not curable, it can be managed.
Andrew McKeon, professor of neurology at the Mayo Clinic reportedly said that treatment is aimed at targeting the nervous system directly so that balance is restored.
Treatment is also targeted at the immune system to stop it from attacking the nervous system.
A report in The Washington Post informs that for patients whose SPS is caused due to an autoimmune condition, treatment may include intravenous immune globulin (IVIG), which is a treatment that uses antibodies to blunt the immune response.
Other treatments include the use of muscle relaxants, anticonvulsants and pain medications for those experiencing pain.
According to NINDS, several symptoms of SPS improve with oral diazepam (an anti-anxiety and muscle relaxant drug) or with meds that alleviate muscle spasms, such as baclofen or gabapentin.
Pavan Tankha, medical director of Comprehensive Pain Recovery at the Cleveland Clinic, reportedly said that patients are also referred to pain psychologists, physical therapists, and other health professionals “to try to improve their overall quality of life and decrease the suffering associated with pain.”
“Pain simply isn’t what you feel; it’s also what it does to you,” he said.
PRIME MINISTER Keir Starmer is facing questions within the Labour party after the sacking of US ambassador Peter Mandelson.
Mandelson was removed last week after Bloomberg published emails showing messages of support he sent following Jeffrey Epstein’s conviction for sex offences. The dismissal comes just ahead of US president Donald Trump’s state visit.
Labour MPs have expressed frustration with the prime minister’s leadership. Labour backbencher Richard Burgon told BBC Radio 4’s Today programme that Starmer would be “gone” if May’s elections in Scotland, Wales and England go badly. “If May’s elections go as people predict and the opinion polls predict, then I think Starmer will be gone at that time,” he said.
Helen Hayes told BBC Radio 4’s Westminster Hour that if the dismissal affected Labour’s performance in the May 2026 local elections, questions about Starmer’s leadership would follow. She said she felt “devastated” about Mandelson but argued he should not have been appointed.
Baroness Smith defended Starmer, telling BBC Breakfast that Burgon had never supported him. She admitted Mandelson’s sacking was “not what we would have wanted” before Trump’s visit but said the prime minister was doing a good job.
Meanwhile, Conservative MP Alex Burghart demanded the release of documents related to Mandelson’s appointment, calling Starmer’s judgement “appalling.” He said the PM ignored warnings about Mandelson’s links to Epstein. Downing Street has said Starmer only learned of the emails on Wednesday and acted immediately.
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Officials greet newly-elected Prime Minister of Nepal's interim government Sushila Karki (R) as she arrives at the prime minister's office in Kathmandu on September 14, 2025. (Photo by PRABIN RANABHAT/AFP via Getty Images)
NEPAL’s new interim prime minister Sushila Karki on Sunday (14) pledged to act on protesters’ calls to end corruption and restore trust in government, as the country struggles with the aftermath of its worst political unrest in decades.
“We have to work according to the thinking of the Gen Z generation,” Karki said in her first address to the nation since taking office on Friday (12). “What this group is demanding is the end of corruption, good governance and economic equality. We will not stay here more than six months in any situation. We will complete our responsibilities and hand over to the next parliament and ministers.”
Karki, 73, a former chief justice known for her independence, was appointed after mass youth-led protests forced the resignation of former prime minister K P Sharma Oli.
The demonstrations began on Monday (8) after the government banned social media, feeding into wider anger over corruption and economic hardship. At least 72 people were killed and more than 1,300 injured, according to government figures, while parliament and government buildings were set on fire.
The new leader held a minute’s silence for those who died before starting work in Singha Durbar, the main government complex in Kathmandu. Parliament has been dissolved, and elections are set for March 5, 2026.
Karki’s appointment followed negotiations led by president Ram Chandra Paudel and army chief General Ashok Raj Sigdel, with input from the youth protest movement. Thousands of young Nepalis had used the Discord messaging app to nominate Karki as their choice for interim leader.
“The situation that I have come in, I have not wished to come here. My name was brought from the streets,” she said.
Behind the movement is Sudan Gurung, a 36-year-old former DJ who founded the non-profit Hami Nepal. Using Discord and Instagram, Gurung and his team mobilised tens of thousands of protesters, even as platforms were blocked. “I will make sure that the power lies with the people and bring every corrupt politician to justice,” Gurung said last week.
Hami Nepal (We are Nepal) activists, many in their 20s, have since become influential in talks over the interim administration. They said they will not take cabinet posts but want to ensure capable young people are involved in decision-making. “The process is being carefully carried out, so that it consists of skilled and capable youth,” the group wrote on Instagram.
Ordinary Nepalis hope the new leadership can deliver. “This government’s list of responsibilities isn’t easy,” said shopkeeper Satya Narayan, 69, in Pharping village near Kathmandu. “It needs to ensure unity and harmony in the country by taking all sections along.”
The unrest has left deep scars. More than 12,500 prisoners escaped during the chaos and remain on the run. Soldiers have now scaled back their presence on the streets, but security challenges remain severe.
Regional leaders, including Indian prime minister Narendra Modi and China’s foreign ministry, have welcomed Karki’s appointment. The Dalai Lama also sent wishes for “success in fulfilling the hopes and aspirations of the people of Nepal in these challenging times.”
For now, young activists who toppled the government are continuing to shape events, with cabinet decisions expected in the coming days. As one protest leader put it: “We don’t want to be politicians. We are only the voice of the nation.”
(Agencies)
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US president Donald Trump and UK prime minister Sir Keir Starmer arrive at Trump International Golf Links on July 28, 2025 in Balmedie, Scotland. (Photo by Jane Barlow-WPA Pool/Getty Images)
THE British government has announced over £1.25 billion ($1.69bn) in fresh investment from major US financial firms, including PayPal, Bank of America, Citigroup and S&P Global, ahead of a state visit by president Donald Trump.
The investment is expected to create 1,800 jobs across London, Edinburgh, Belfast and Manchester, and deepen transatlantic financial ties, the Department for Business and Trade said.
Bank of America will launch its first operation in Northern Ireland, creating up to 1,000 jobs in Belfast. Citigroup plans to invest £1.1bn across its UK operations, including a further commitment to growing its presence in Northern Ireland.
S&P Global will invest over £4 million in Manchester, supporting 200 permanent roles, while BlackRock is expected to allocate £7m to the UK market next year and has opened a new office in Edinburgh, nearly doubling its local workforce.
"These investments reflect the strength of our enduring 'golden corridor' with one of our closest trading partners," said Britain's trade minister, Peter Kyle.
Chancellor Rachel Reeves said the investments would "kickstart the growth that is essential to putting money in working people's pockets across every part of the UK."
The government said the deals line up £20bn in trade between Britain and the US.
Also on Saturday (13), the British Embassy in Washington said the countries were planning to sign a technology agreement in the coming days to bolster collaboration between their trillion-dollar tech sectors.
Trump is to fly to Britain on Tuesday (16) for his second state visit, which is expected to last three days.
(Reuters)
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Protesters wave Union Jack and St George's England flags during the "Unite The Kingdom" rally on Westminster Bridge by the Houses of Parliament on September 13, 2025 in London, England. (Photo by Christopher Furlong/Getty Images)
MORE THAN 100,000 protesters marched through central London on Saturday (13), carrying flags of England and Britain and scuffling with police in one of the UK's biggest right-wing demonstrations of modern times.
London's Metropolitan Police said the "Unite the Kingdom" march, organised by anti-immigrant activist Tommy Robinson, was attended by nearly 150,000 people, who were kept apart from a "Stand Up to Racism" counter-protest attended by around 5,000.
The police appeared to be taken by surprise by the size of the turnout, describing the rally as "too big to fit into Whitehall," a wide street lined with government buildings, on the approved route of the march.
Police trying to prevent protesters veering from the route faced "unacceptable violence," the force said, describing officers being kicked and punched and facing hurled bottles, flares and other projectiles.
The police said 26 officers were injured, including four seriously. Arrests totalled 25, which the force said was "just the start."
"We are identifying those who were involved in the disorder and they can expect to face robust police action in the coming days and weeks," assistant commissioner Matt Twist said.
The march brought a culmination to a highly charged summer in Britain that included protests staged outside hotels housing migrants.
Demonstrators carried the Union flag of Britain and the red and white St George's Cross of England, while others brought American and Israeli flags and wore the "Make America Great Again" or MAGA hats of US president Donald Trump. They chanted slogans critical of prime minister Keir Starmer and carried placards including some saying "send them home." Some attendees brought children.
Anti-Racism protesters come out in support of refugees outside the Cladhan Hotel on September 13, 2025 in Falkirk, Scotland. (Photo by Jeff J Mitchell/Getty Images)
"Today is the spark of a cultural revolution in Great Britain, this is our moment," Robinson said in an address to supporters, saying they had shown "a tidal wave of patriotism."
In a video link to the rally, US billionaire Elon Musk, who has intervened in British politics to support Robinson and other far-right figures, called for a change of government in Britain. He said the British public were scared to exercise their free speech.
Robinson, whose real name is Stephen Yaxley-Lennon, describes himself as a journalist exposing state wrongdoing. Britain's biggest anti-immigrant political party, Reform UK, which has topped opinion polls in recent months, has kept its distance from Robinson, who has several criminal convictions.
"We want our country back, we want our free speech back on track," said Sandra Mitchell, a supporter attending the rally.
"They need to stop illegal migration into this country," she said. "We believe in Tommy."
At the counter-protest, Ben Hetchin, a teacher, said: "The idea of hate is dividing us and I think the more that we welcome people the stronger we are as a country."
Police said they had more than 1,600 officers deployed across London on Saturday, including 500 brought in from other forces. In addition to policing the two demonstrations, the London force was stretched by high-profile soccer matches and concerts.
Immigration has become the dominant political issue in Britain, eclipsing concerns over a faltering economy, as the country faces a record number of asylum claims. More than 28,000 migrants have arrived in small boats across the Channel so far this year.
Red and white English flags have proliferated along streets and been painted on roads. Supporters call it a spontaneous campaign of national pride, but anti-racism campaigners see a message of hostility to foreigners.
Anti-racism charity Hope Not Hate, which has monitored such rallies for more than a decade, said "a number of well known far-right extremists" including Robinson spoke on-stage and were among the crowds.
Joe Mulhall, its director of research, told the BBC it was "probably... the largest far-right demonstration ever in Britain".
King's College London assistant public policy professor Georgios Samaras agreed, saying it showed "multiple factions within the far-right" as well as newcomers had converged in London.
It comes amid growing anti-immigration sentiment, as Brexit supporter Nigel Farage's hard-right Reform UK leads in polls and protesters target hotels used to house asylum seekers.
It also follows anti-immigration riots last year in numerous towns and cities, which Robinson was accused of fuelling with incendiary online posts.
(Agencies)
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Piyush Goyal recalled that in February, Narendra Modi and Donald Trump had instructed their trade ministers to conclude the first phase of the bilateral trade agreement (BTA) by November 2025. (Photo: Getty Images)
INDIA’s commerce and industry minister Piyush Goyal on Thursday said that negotiations on the proposed trade agreement between India and the United States, which began in March, are progressing in a positive atmosphere and both sides are satisfied with the discussions.
He recalled that in February, Indian prime minister Narendra Modi and US president Donald Trump had instructed their trade ministers to conclude the first phase of the bilateral trade agreement (BTA) by November 2025.
“Discussions have been going on in a positive atmosphere with seriousness since March. It is progressing, and both the countries are satisfied with the progress,” Goyal told reporters. On Wednesday, he had also said that India is in “active dialogue” with the United States.
Trump this week said there would be “no difficulty” for the two countries to reach a successful conclusion and that he looked forward to speaking with his “very good friend” Modi in the coming weeks. In a post on Truth Social, he wrote he was “pleased to announce that India, and the United States of America, are continuing negotiations to address the Trade Barriers between our two Nations.”
Modi responded on X, welcoming Trump’s statement and expressing confidence that the negotiations would help unlock the potential of the partnership. He said India and the US are close friends and natural partners and are working to conclude the discussions at the earliest.
The two countries have completed five rounds of negotiations since March. The sixth round, scheduled to take place in India last month, was deferred after Washington imposed an additional 25 per cent tariff on Indian goods over purchases of Russian crude oil.
The aim of the pact is to more than double bilateral trade in goods and services to USD 500 billion by 2030 from the current USD 191 bn. Trade ties have been strained due to tariffs, with the US imposing a 50 per cent import duty on Indian goods from August 27. The move has hit exports from labour-intensive sectors such as shrimp, textiles, leather and footwear. India has described the tariffs as unfair, unjustified and unreasonable.
Talks have also been delayed over US demands for greater access in sensitive sectors such as agriculture and dairy. India has said repeatedly that it will not compromise the interests of small and marginal farmers and cattle rearers.
The US is India’s largest trading partner. In 2024-25, bilateral trade in goods was USD 131.8 bn, with India’s exports at USD 86.5 bn and imports at USD 45.3 bn. The US is also the third-largest investor in India, with foreign direct investment of USD 76.26 bn between April 2000 and June 2025, accounting for 10 per cent of India’s total FDI inflows.
On protests in Nepal, Goyal said the Indian government is monitoring the situation and working to bring back Indian citizens stranded there. He added that the Indian mission in Nepal is ready to provide support and expressed hope for normalcy to return soon.