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Novartis, US agree to malaria drug trial against COVID-19

SWISS drugmaker Novartis on Monday (20) reached an agreement with the US regulators to hold a randomised trial of generic malaria drug hydroxychloroquine against COVID-19 disease in 440 hospitalised patients.

The decades-old medicine has received US Food and Drug Administration (FDA) emergency use authorisation for COVID-19 disease, but so far there is no scientific proof it helps those afflicted.


"We recognise the importance of answering the scientific question of whether hydroxychloroquine will be beneficial for patients with COVID-19 disease,” said John Tsai, Novartis's top drug developer.

The drug, also used to treat lupus and rheumatoid arthritis, has been promoted by president Donald Trump, with some worried the administration's advocacy for an unproven medicine for COVID-19 has short-circuited the oversight process.

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Meryl Streep turns 77: Seven milestones that shaped the Hollywood icon’s remarkable career

Few actors have managed to remain at the top of their profession for as long as Meryl Streep

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Meryl Streep turns 77: Seven milestones that shaped the Hollywood icon’s remarkable career

Highlights

  • Meryl Streep celebrates her 77th birthday on 22 June.
  • She holds the record for the most acting Oscar nominations.
  • Her career spans more than five decades across film, television and theatre.
  • From early setbacks to record-breaking success, Streep has remained one of Hollywood’s most respected performers.

Few actors have managed to remain at the top of their profession for as long as Meryl Streep. Acclaimed for her versatility, emotional depth and ability to master vastly different characters, she has built a career that has influenced generations of performers. As the Hollywood legend turns 77, here are seven milestones that helped shape her extraordinary journey.

1. A Yale education laid the foundation for her career

Long before she became one of Hollywood’s most celebrated stars, Streep was honing her craft at the Yale School of Drama. She earned a Master of Fine Arts degree and immersed herself in theatre, developing the technical skills and discipline that would later define her performances. Her years at Yale helped prepare her for a career that would demand both artistic range and remarkable consistency.

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