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Novartis, US agree to malaria drug trial against COVID-19

SWISS drugmaker Novartis on Monday (20) reached an agreement with the US regulators to hold a randomised trial of generic malaria drug hydroxychloroquine against COVID-19 disease in 440 hospitalised patients.

The decades-old medicine has received US Food and Drug Administration (FDA) emergency use authorisation for COVID-19 disease, but so far there is no scientific proof it helps those afflicted.


"We recognise the importance of answering the scientific question of whether hydroxychloroquine will be beneficial for patients with COVID-19 disease,” said John Tsai, Novartis's top drug developer.

The drug, also used to treat lupus and rheumatoid arthritis, has been promoted by president Donald Trump, with some worried the administration's advocacy for an unproven medicine for COVID-19 has short-circuited the oversight process.

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Karan Johar

Dharma Productions scouts fresh faces after 500 auditions

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Karan Johar’s Dharma Productions chooses outsiders after 500-audition hunt for newcomers in Bollywood

Highlights

  • Dharma Productions to introduce a boy and girl with no industry links
  • Over 500 auditions held across India
  • Taran Adarsh, Sumit Kadel confirm the major talent search
  • Move seen as shift from star kids to fresh faces
  • Identities of debutants yet to be revealed

Karan Johar and Dharma Productions are betting big on fresh talent. The studio is launching two newcomers in Bollywood after what’s being called its largest-ever talent hunt, which spanned more than 500 auditions from across India. The aim, insiders say, is to find raw, authentic performers, not familiar surnames.

Karan Johar Dharma Productions scouts fresh faces after 500 auditions Getty Images

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